Problems Respiration: Respiration issues is usually serious, especially if Alcoholic beverages or other sedatives are put together.

Patients addressed with flumazenil ought to be monitored for re-sedation, respiratory despair, and other residual benzodiazepine effects for an ideal time period just after therapy. The prescriber need to concentrate on a threat of seizure in Affiliation with flumazenil treatment, significantly in lengthy-expression benzodiazepine customers As well as in cyclic antidepressant overdose. The whole flumazenil offer insert should be consulted prior to use.

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Use with digoxin: enhance the possibility of digoxin toxicity. Use with CYP3A inhibitors (except ritonavir): increase the possibility of adverse reactions of alprazolam. Use with CYP3A inducers: raise the danger of lessened efficacy of Xanax.

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